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Names

Troparil
β-CPT
(-)-2β-Carbomethoxy-3β-phenyltropane
WIN 35,065-2

IUPAC name

Methyl (2S,3S)-8-methyl-3-phenyl-8-azabicyclo[3.2.1]octane-2-carboxylate

ID 2977 · Formula C₁₆H₂₁NO₂ · Molecular weight 259.343

InChI InChI=1S/C16H21NO2/c1-17-12-8-9-14(17)15(16(18)19-2)13(10-12)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3/t12?,13-,14?,15+/m1/s1

InChI Key OMBOXYLBBHNWHL-JYVUQVBGSA-N This stereoisomer Any stereoisomer

SMILES COC(=O)[C@@H]1C2CCC(N2C)C[C@@H]1c1ccccc1

ChemSpider 8199338
PubChem 10023767
Wikipedia Troparil

Roman, DL; Saldaña, SN; Nichols, DE; Carroll, FI; Barker, EL. Distinct molecular recognition of psychostimulants by human and Drosophila serotonin transporters J. Pharmacol. Exp. Ther., 1 Jan 2004, 308 (2), 679–687. 519 kB. https://doi.org/10.1124/jpet.103.057836

Walline, CC; Nichols, DE; Carroll, FI; Barker, EL. Comparative molecular field analysis using selectivity fields reveals residues in the third transmembrane helix of the serotonin transporter associated with substrate and antagonist recognition J. Pharmacol. Exp. Ther., 1 Jun 2008, 325 (3), 791–800. 269 kB. https://doi.org/10.1124/jpet.108.136200 #(–)-2β-Carbomethoxy-3β-phenyltro

Casale, JF; Hays, PA. Characterization of 2β-(1,2,4-oxadiazol-5-methyl)-3β-phenyltropane (“RTI-126”) Microgram J., 1 Jan 2011, 8 (1), 3–11. 682 kB. #3 GC,MS,NMR,IR

Nichols, DE. CNS Stimulants In Burger's Medicinal Chemistry and Drug Discovery; Abraham, DJ, Ed., John Wiley & Sons, Inc., 29 Jan 2010; pp 89–120. 1.8 MB. https://doi.org/10.1002/0471266949.bmc243 #39

Propranolol

Nortilidine

9648

9660

2α-Carbomethoxy-3β-phenyltropane

Ramelteon

13011

7 Dec 2019 · · Isomer Design