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IUPAC name

1-Methyl-8-(trifluoromethyl)-2,3,4,5-tetrahydro-1H-3-benzazepine

ID 2742 · Formula C₁₂H₁₄F₃N · Molecular weight 229.241

InChI InChI=1S/C12H14F3N/c1-8-7-16-5-4-9-2-3-10(6-11(8)9)12(13,14)15/h2-3,6,8,16H,4-5,7H2,1H3

InChI Key GBYLNYMTYZRQLE-UHFFFAOYSA-N This stereoisomer Any stereoisomer

SMILES CC1CNCCc2c1cc(cc2)C(F)(F)F

ChemSpider 8280735
PubChem 10105208

Smith, BM; Smith, JM; Tsai, JH; Schultz, JA; Gilson, CA; Estrada, SA; Chen, RR; Park, DM; Prieto, EB; Gallardo, CS; Sengupta, D; Thomsen, WJ; Saldana, HR; Whelan, KT; Menzaghi, F; Webb, RR; Beeley, NRA. Discovery and SAR of new benzazepines as potent and selective 5-HT_2C receptor agonists for the treatment of obesity Bioorg. Med. Chem. Lett., 1 Mar 2005, 15 (5), 1467–1470. 122 kB. https://doi.org/10.1016/j.bmcl.2004.12.080 #17c

Smith, BM; Smith, JM; Tsai, JH; Schultz, JA; Gilson, CA; Estrada, SA; Thomsen, WJ. Discovery and Structure−Activity Relationship of (1R)-8-Chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a Selective Serotonin 5-HT_2C Receptor Agonist for the Treatment of Obesity J. Med. Chem., 1 Jan 2008, 51 (2), 305–313. 158 kB. https://doi.org/10.1021/jm0709034 #7f,g,h MS,NMR

ETAI · Ethyltrifluoromethylaminoindane

7 Dec 2019 · · Isomer Design