Wallach, J; Kavanagh, PV; McLaughlin, G; Morris, N; Power, JD; Elliott, SP; Mercier, MS; Lodge, D; Morris, H; Dempster, NM; Brandt, SD. Preparation and characterization of the ‘research chemical’ diphenidine, its pyrrolidine analogue, and their 2,2-diphenylethyl isomers. Drug Test. Anal., 1 May 2015, 7 (5), 358-367. 632 kB. https://doi.org/10.1002/dta.1689
EMCDDA. Report on the risk assessment of 2-(3-methoxyphenyl)-2-(ethylamino)cyclohexanone (methoxetamine), European Monitoring Centre for Drugs and Drug Addiction, Lisbon, . 1.3 MB. #Methoxetamine
Morris, H; Wallach, J. From PCP to MXE: A comprehensive review of the non-medical use of dissociative drugs. Drug Test. Anal., 1 Jul 2014, 6 (7-8), 614-632. 942 kB. https://doi.org/10.1002/dta.1620 #Methoxetamine, MXE
Colestock, T; Wallach, J; Mansi, M; Filemban, N; Morris, H; Elliott, SP; Westphal, F; Brandt, SD; Adejare, A. Syntheses, analytical and pharmacological characterizations of the ‘legal high’ 4-[1-(3-methoxyphenyl)cyclohexyl]morpholine (3-MeO-PCMo) and analogues. Drug Test. Anal., 1 Feb 2018, 10 (2), 272-283. 1.3 MB. https://doi.org/10.1002/dta.2213
Morris, H; Wallach, J. Arylcyclohexylamines. Psymposium 2014, 27 Oct 2015. 39:47. Psymposia Big hug to W. Snow for providing the video. Unfortunately I just cannot seem to make it work. It may be a bug in my code. For now, the link points to YouTube.
EMCDDA. New drugs in Europe, 2014, European Monitoring Centre for Drugs and Drug Addiction, Lisbon, 1 Jul 2015. 879 kB.
EMCDDA. New drugs in Europe, 2013, European Monitoring Centre for Drugs and Drug Addiction, Lisbon, 1 Jul 2014. 311 kB.
EMCDDA. New drugs in Europe, 2011, European Monitoring Centre for Drugs and Drug Addiction, Lisbon, 1 Apr 2012. 401 kB.
EMCDDA. New drugs in Europe, 2010, European Monitoring Centre for Drugs and Drug Addiction, Lisbon, 1 May 2011. 700 kB.
Zawilska, JB; Andrzejczak, D. Next generation of novel psychoactive substances on the horizon – A complex problem to face. Drug Alcohol Depend., 1 Jan 2015, 157, 1-17. 3.0 MB. https://doi.org/10.1016/j.drugalcdep.2015.09.030
Roth, BL; Gibbons, S; Arunotayanun, W; Huang, X; Setola, V; Treble, R; Iversen, L. The ketamine analogue methoxetamine and 3- and 4-methoxy analogues of phencyclidine are high affinity and selective ligands for the glutamate NMDA receptor. PLoS ONE, 19 Mar 2013, 8 (3), e59334. 453 kB. https://doi.org/10.1371/journal.pone.0059334 #Methoxetamine
Vidal Giné, C; Espinosa, IF; Vilamala, MV. New psychoactive substances as adulterants of controlled drugs. A worrying phenomenon? Drug Test. Anal., 1 Jul 2014, 6 (7-8), 819-824. 113 kB. https://doi.org/10.1002/dta.1610
Zanda, MT; Fadda, P; Chiamulera, C; Fratta, W; Fattore, L. Methoxetamine, a novel psychoactive substance with serious adverse pharmacological effects: a review of case reports and preclinical findings. Behav. Pharmacol., 1 Sep 2016, 27 (6), 489–496. 313 kB. https://doi.org/10.1097/FBP.0000000000000241 #MXE
Wallach, J; Brandt, SD. Phencyclidine-based new psychoactive substances. In New Psychoactive Substances: Pharmacology, Clinical, Forensic and Analytical Toxicology; Maurer, HH; Brandt, SD, Eds., Springer, Berlin, Heidelberg, 1 Jan 2018; pp 261-303. 515 kB. https://doi.org/10.1007/164_2018_124 #MXE
Yoshida, M; Suzuki, J; Nakajima, J; Nagashima, M; Takahashi, M; Uemura, N; Kanai, C; Moriyasu, T; Hamano, T; Nakae, D. Analysis of illegal drugs purchased in the fiscal year 2011. Ann. Rep. Tokyo Metr. Inst. P. H., 1 Jan 2012, 63 111–124. 575 kB. #Methoxetamine MS,NMR,UV
Casale, JF; Hays, PA; Berrier, A. The characterization of 2-(3-methoxyphenyl)-2-(ethylamino)cyclohexanone (methoxetamine). Microgram J., 1 Jan 2012, 9 (1), 3–17. 1.9 MB. #Methoxetamine GC,MS,NMR,IR
Wallach, J; Brandt, SD. 1,2-Diarylethylamine- and ketamine-based new psychoactive substances. In New Psychoactive Substances: Pharmacology, Clinical, Forensic and Analytical Toxicology; Maurer, HH; Brandt, SD, Eds., Springer, Berlin, Heidelberg, 1 Jan 2018; pp 305-352. 593 kB. https://doi.org/10.1007/164_2018_148 #MXE
De Paoli, G; Brandt, SD; Wallach, J; Archer, RP; Pounder, DJ. From the street to the laboratory: Analytical profiles of methoxetamine, 3-methoxyeticyclidine and 3-methoxyphencyclidine and their determination in three biological matrices. J. Anal. Toxicol., 1 Jun 2013, 37 (5), 277–283. 264 kB. https://doi.org/10.1093/jat/bkt023 #MXE GC,LC,MS,NMR,UV
Kronstrand, R; Guerrieri, D; Vikingsson, S; Wohlfarth, A; Gréen, H. Fatal poisonings associated with new psychoactive substances. In New Psychoactive Substances: Pharmacology, Clinical, Forensic and Analytical Toxicology; Maurer, HH; Brandt, SD, Eds., Springer, Berlin, Heidelberg, 1 Jan 2018; pp 495–541. 477 kB. https://doi.org/10.1007/164_2018_110 #Methoxetamine
Kraemer, M; Boehmer, A; Madea, B; Maas, A. Death cases involving certain new psychoactive substances: A review of the literature. Forensic Sci. Int., 1 May 2019, 298, 186–267. 6.7 MB. https://doi.org/10.1016/j.forsciint.2019.02.021 #Methoxetamine
Bertron, JL; Seto, M; Lindsley, CW. DARK classics in chemical neuroscience: Phencyclidine (PCP). ACS Chem. Neurosci., 17 Oct 2018, 9 (10), 2459-2474. 9.9 MB. https://doi.org/10.1021/acschemneuro.8b00266 #8
Hägele, JS; Basrak, M; Schmid, MG. Enantioselective separation of novel psychoactive substances using a Lux® AMP 3 μm column and HPLC-UV. J. Pharm. Biomed. Anal., 5 Feb 2020, 179, 112967. 3.6 MB. https://doi.org/10.1016/j.jpba.2019.112967 #E5 LC
Frison, G; Zamengo, L; Zancanaro, F; Tisato, F; Traldi, P. Characterization of the designer drug deschloroketamine (2-methylamino-2-phenylcyclohexanone) by gas chromatography/mass spectrometry, liquid chromatography/high-resolution mass spectrometry, multistage mass spectrometry, and nuclear magnetic resonance. Rapid Commun. Mass Spectrom., 15 Jan 2016, 30 (1), 151–160. 1.7 MB. https://doi.org/10.1002/rcm.7425 #Methoxetamine MS,NMR,other
Tanaka, R; Kawamura, M; Mizutani, S; Hakamatsuka, T; Kikura-Hanajiri, R. Identification of three arylcyclohexylamines (MXPr, MXiPr, and DMXE) in illegal products. Yakugaku Zasshi, 1 Jan 2022, 142 (6), 675–681. 1.0 MB. https://doi.org/10.1248/yakushi.21-00235 #MXE GC,LC,MS,NMR,UV
Irie, T; Yanase, Y; Demizu, Y; Usami, M; Kikura-Hanajiri, R. Derivatives of methoxetamine and major methoxetamine metabolites potently block NMDA receptors. J. Pharmacol. Sci., 1 Dec 2022, 150 (4), 233–243. 2.9 MB. https://doi.org/10.1016/j.jphs.2022.09.005 #MXE