- 5F-MDMB-PINACA
- 5F-ADB
- MDMB-5F-PINACA
- Methyl N-[1-(5-fluoropentyl)-1H-indazole-3-carbonyl]-3-methyl-L-valinate
- Methyl (2S)-2-{[1-(5-fluoropentyl)-1H-indazole-3-carbonyl]amino}-3,3-dimethylbutanoate
Longworth, M; Banister, SD; Boyd, R; Kevin, RC; Connor, M; McGregor, IS; Kassiou, M. The pharmacology of cumyl-carboxamide synthetic cannabinoid new psychoactive substances (NPS) CUMYL-BICA, CUMYL-PICA, CUMYL-5F-PICA, CUMYL-5F-PINACA, and their analogues ACS Chem. Neurosci., 9 Aug 2017, 8 (10), 2159-2167. 1.7 MB. https://doi.org/10.1021/acschemneuro.7b00267 #6
Mogler, L; Franz, F; Rentsch, D; Angerer, V; Weinfurtner, G; Longworth, M; Banister, SD; Kassiou, M; Moosmann, B; Auwärter, V. Detection of the recently emerged synthetic cannabinoid 5F–MDMB-PICA in ‘legal high’ products and human urine samples Drug Test. Anal., 1 Jan 2018, 10 (1), 196-205. 1.0 MB. https://doi.org/10.1002/dta.2201 MS
EMCDDA. New drugs in Europe, 2016, European Monitoring Centre for Drugs and Drug Addiction, Lisbon, 1 May 2017. 489 kB.
EMCDDA. New drugs in Europe, 2015, European Monitoring Centre for Drugs and Drug Addiction, Lisbon, 1 May 2016. 1.0 MB. #1
Kaizaki-Mitsumoto, A; Noguchi, N; Yamaguchi, S; Odanaka, Y; Matsubayashi, S; Kumamoto, H; Fukuhara, K; Funada, M; Wada, K; Numazawa, S. Three 25-NBOMe-type drugs, three other phenethylamine-type drugs (25I-NBMD, RH34, and escaline), eight cathinone derivatives, and a phencyclidine analog MMXE, newly identified in ingredients of drug products before they were sold on the drug market Forensic Toxicol., 1 Jan 2016, 34 (1), 108–114. 854 kB. https://doi.org/10.1007/s11419-015-0293-6 MS,NMR
Hess, C; Murach, J; Krueger, L; Scharrenbroch, L; Unger, M; Madea, B; Sydow, K. Simultaneous detection of 93 synthetic cannabinoids by liquid chromatography-tandem mass spectrometry and retrospective application to real forensic samples Drug Test. Anal., 1 May 2017, 9 (5), 721-733. 267 kB. https://doi.org/10.1002/dta.2030 #5 fluoro ADB LC,MS
Angerer, V; Bisel, P; Moosmann, B; Westphal, F; Auwärter, V. Separation and structural characterization of the new synthetic cannabinoid JWH-018 cyclohexyl methyl derivative NE-CHMIMO using flash chromatography, GC-MS, IR and NMR spectroscopy Forensic Sci. Int., 1 Sep 2016, 266, e93–e98. 1.1 MB. https://doi.org/10.1016/j.forsciint.2016.05.031 MS,NMR,IR
Abbate, V; Schwenk, M; Presley, BC; Uchiyama, N. The ongoing challenge of novel psychoactive drugs of abuse. Part I. Synthetic cannabinoids (IUPAC Technical Report) Pure Appl. Chem., 28 Aug 2018, 90 (8), 1255–1282. 1.0 MB. https://doi.org/10.1515/pac-2017-0605 #8. 5F-ADB
EMCDDA. Report on the risk assessment of methyl 2-{[1-(5-fluoropentyl)-1H-indazole-3-carbonyl]amino}-3,3-dimethylbutanoate (5F-MDMB-PINACA), European Monitoring Centre for Drugs and Drug Addiction, Lisbon, 1 Jul 2018. 736 kB. #5F-MDMB-PINACA IR,UV
Banister, SD; Connor, M. The chemistry and pharmacology of synthetic cannabinoid receptor agonist new psychoactive substances: Evolution In New Psychoactive Substances: Pharmacology, Clinical, Forensic and Analytical Toxicology; Maurer, HH; Brandt, SD, Eds., Springer, Berlin, Heidelberg, 1 Jan 2018; pp 191-226. 1.2 MB. https://doi.org/10.1007/164_2018_144 #69
Kronstrand, R; Guerrieri, D; Vikingsson, S; Wohlfarth, A; Gréen, H. Fatal poisonings associated with new psychoactive substances In New Psychoactive Substances: Pharmacology, Clinical, Forensic and Analytical Toxicology; Maurer, HH; Brandt, SD, Eds., Springer, Berlin, Heidelberg, 1 Jan 2018; pp 495–541. 477 kB. https://doi.org/10.1007/164_2018_110 #5F-ADB
Ernst, L; Langer, N; Bockelmann, A; Salkhordeh, E; Beuerle, T. Identification and quantification of synthetic cannabinoids in ‘spice-like’ herbal mixtures: Update of the German situation in summer 2018 Forensic Sci. Int., 1 Jan 2019, 294, 96–102. 924 kB. https://doi.org/10.1016/j.forsciint.2018.11.001 #2 MS,NMR,IR,UV
Kraemer, M; Boehmer, A; Madea, B; Maas, A. Death cases involving certain new psychoactive substances: A review of the literature Forensic Sci. Int., 1 May 2019, 298, 186–267. 6.7 MB. https://doi.org/10.1016/j.forsciint.2019.02.021 #5F-ADB
Patel, M; Manning, JJ; Finlay, DB; Javitch, JA; Banister, SD; Grimsey, NL; Glass, M. Signalling profiles of a structurally diverse panel of synthetic cannabinoid receptor agonists Biochem. Pharmacol., 1 May 2020, 175 113871. 1.9 MB. https://doi.org/10.1016/j.bcp.2020.113871 #5F-ADB
Wouters, E; Walraed, J; Robertson, MJ; Meyrath, M; Szpakowska, M; Chevigné, A; Skiniotis, G; Stove, C. Assessment of biased agonism among distinct synthetic cannabinoid receptor agonist scaffolds ACS Pharmacol. Transl. Sci., 10 Apr 2020, 3 (2), 285–295. 2.0 MB. https://doi.org/10.1021/acsptsci.9b00069 #14
Kikura-Hanajiri, R. New designer drugs in japan In Neuropathology of Drug Addictions and Substance Misuse; Preedy, VR, Ed., Academic Press, 1 Jan 2016; pp 1055–1065. 682 kB. https://doi.org/10.1016/B978-0-12-800212-4.00097-2 #5F-ADB
Cannaert, A; Sparkes, E; Pike, E; Luo, JL; Fang, A; Kevin, RC; Ellison, R; Gerona, R; Banister, SD; Stove, CP. Synthesis and in vitro cannabinoid receptor 1 activity of recently detected synthetic cannabinoids 4F-MDMB-BICA, 5F-MPP-PICA, MMB-4en-PICA, CUMYL-CBMICA, ADB-BINACA, APP-BINACA, 4F-MDMB-BINACA, MDMB-4en-PINACA, A-CHMINACA, 5F-AB-P7AICA, 5F-MDMB-P7AICA, and 5F-AP7AICA ACS Chem. Neurosci., 16 Dec 2020, 11 (24), 4434–4446. 3.7 MB. https://doi.org/10.1021/acschemneuro.0c00644 #8a MS,NMR,IR,TLC
De Morais, J; Brandt, SD; Jorge, R; Christie, R; Gallegos, A; Sedefov, R; Evans-Brown, M. EMCDDA technical report on the new psychoactive substance methyl 3,3-dimethyl-2-{[1-(pent-4-en-1-yl)-1H-indazole-3-carbonyl]amino}butanoate (MDMB-4en-PINACA), 21 Dec 2020. 1.1 MB. #5F-MDMB-PINACA
Åstrand, A; Guerrieri, D; Vikingsson, S; Kronstrand, R; Green, H. In vitro characterization of new psychoactive substances at the μ-opioid, CB1, 5HT1A, and 5-HT2A receptors—On-target receptor potency and efficacy, and off-target effects Forensic Sci. Int., 1 Dec 2020, 317, 110553. 1.7 MB. https://doi.org/10.1016/j.forsciint.2020.110553 #5F-ADB
Antonides, LH; Brignall, RM; Costello, A; Ellison, J; Firth, SE; Gilbert, N; Groom, BJ; Hudson, SJ; Hulme, MC; Marron, J; Pullen, ZA; Robertson, TBR; Schofield, CJ; Williamson, DC; Kemsley, EK; Sutcliffe, OB; Mewis, RE. Rapid identification of novel psychoactive and other controlled substances using low-field 1H NMR spectroscopy ACS Omega, 30 Apr 2019, 4 (4), 7103–7112. 1.3 MB. https://doi.org/10.1021/acsomega.9b00302 #5F-ADB NMR
Wouters, E; Mogler, L; Cannaert, A; Auwärter, V; Stove, C. Functional evaluation of carboxy metabolites of synthetic cannabinoid receptor agonists featuring scaffolds based on L‐valine or L‐ tert ‐leucine Drug Test. Anal., 1 Aug 2019, 11 (8), 1183–1191. 1.4 MB. https://doi.org/10.1002/dta.2607 #2
Ametovski, A; Macdonald, C; Manning, JJ; Haneef, SAS; Santiago, M; Martin, L; Sparkes, E; Reckers, A; Gerona, RR; Connor, M; Glass, M; Banister, SD. Exploring stereochemical and conformational requirements at cannabinoid receptors for synthetic cannabinoids related to SDB-006, 5F-SDB-006, CUMYL-PICA, and 5F-CUMYL-PICA ACS Chem. Neurosci., 4 Nov 2020, 11 (21), 3672–3682. 3.5 MB. https://doi.org/10.1021/acschemneuro.0c00591 #4 MS,NMR
Andrews, R; Jorge, R; Christie, R; Gallegos, A. From JWH‐018 to OXIZIDS: Structural evolution of synthetic cannabinoids in the European Union from 2008 to present day Drug Test. Anal., 1 Apr 2023, 15 (4), 378–387. 1.2 MB. https://doi.org/10.1002/dta.3422 #5F-MDMB-PINACA