Exploring FLY. To explore a different substance…

Names:
FLY · H-FLY · 1-(2,3,6,7-Tetrahydrofuro[2,3-f][1]benzofuran-4-yl)propan-2-amine
IUPAC name:
1-(2,3,6,7-Tetrahydrobenzo[1,2-b:4,5-b′]difuran-4-yl)propan-2-amine
ID: 2022 · Formula: C13H17NO2 · Molecular weight: 219.28
InChI: InChI=1S/C13H17NO2/c1-8(14)6-11-10-3-5-15-12(10)7-9-2-4-16-13(9)11/h7-8H,2-6,14H2,1H3

Parker, MA; Kurrasch, DM; Nichols, DE. The role of lipophilicity in determining binding affinity and functional activity for 5-HT2A receptor ligands. Bioorg. Med. Chem., 1 Jan 2008, 16 (8), 4661–4669. 296 kB. http://dx.doi.org/10.1016/j.bmc.2008.02.033

Chambers, JJ; Kurrasch-Orbaugh, DM; Parker, MA; Nichols, DE. Enantiospecific synthesis and pharmacological evaluation of a series of super-potent, conformationally restricted 5-HT2A/2C receptor agonists. J. Med. Chem., 1 Jan 2001, 44 (6), 1003–1010. 337 kB. http://dx.doi.org/10.1021/jm000491y

Monte, AP; Marona-Lewicka, D; Parker, MA; Wainscott, DB; Nelson, DL; Nichols, DE. Dihydrobenzofuran analogues of hallucinogens. 3. 1 Models of 4-substituted (2,5-dimethoxyphenyl)alkylamine derivatives with rigidified methoxy groups. J. Med. Chem., 1 Jan 1996, 39 (15), 2953–2961. 290 kB. http://dx.doi.org/10.1021/jm960199j

Heim, R. Synthesis and pharmacology of potent 5-HT2A receptor agonists with N-2-methoxybenzyl partial structure. SC. D. Thesis, Freie Universität, Berlin, 1 Jan 2004. In German.

2C-FLY
4C-FLY
DOB-FLY
DOM-FLY
TFM-FLY
I-FLY
706
707
708
709
710
711
712
713
714
715
716
DMA-FLEA
DMA-GNAT
MDAL
2C-D-FLY
DOYN
DOMAD
2C-FLEA
2C-GNAT
2768
2C-FLY
4C-FLY
DOB-FLY
DOM-FLY
TFM-FLY
I-FLY
706
707
708
709
710
711
712
713
714
715
716
DMA-FLEA
DMA-GNAT
MDAL
2C-D-FLY
DOYN
DOMAD
2C-FLEA
2C-GNAT
2768
19 November 2017 · Creative Commons BY-NC-SA ·