- 4-MTA
- MTA
- 4-Methylthioamphetamine
Marona-Lewicka, D; Rhee, G; Sprague, JE; Nichols, DE. Psychostimulant-like effects of p-fluoroamphetamine in the rat. Eur. J. Pharmacol., 12 Dec 1995, 287 (2), 105–113. 965 kB. https://doi.org/10.1016/0014-2999(95)00478-5
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Błachut, D; Wojtasiewicz, K; Czarnocki, Z; Szukalski, B. The analytical profile of some 4-methylthioamphetamine (4-MTA) homologues. Forensic Sci. Int., 20 Nov 2009, 192 (1–3), 98–114. 683 kB. https://doi.org/10.1016/j.forsciint.2009.08.009
Scorza, MC; Carrau, C; Silveira, R; Zapata-Torres, G; Cassels, BK; Reyes-Parada, M. Monoamine oxidase inhibitory properties of some methoxylated and alkylthio amphetamine derivatives. Biochem. Pharmacol., 15 Dec 1997, 54 (12), 1361–1369. 697 kB. https://doi.org/10.1016/S0006-2952(97)00405-X #5 MTA
Vilches-Herrera, M; Miranda-Sepúlveda, J; Rebolledo-Fuentes, M; Fierro, A; Lühr, S; Iturriaga-Vasquez, P; Cassels, BK; Reyes-Parada, M. Naphthylisopropylamine and N-benzylamphetamine derivatives as monoamine oxidase inhibitors. Bioorg. Med. Chem., 15 Mar 2009, 17 (6), 2452–2460. 509 kB. https://doi.org/10.1016/j.bmc.2009.01.074
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EMCDDA. Report on the risk assessment of 4-MTA, European Monitoring Centre for Drugs and Drug Addiction, Lisbon, . 79 kB. #4-MTA
Cloonan, SM; Keating, JJ; Corrigan, D; O’Brien, JE; Kavanagh, PV; Williams, DC; Meegan, MJ. Synthesis and in vitro toxicity of 4-MTA, its characteristic clandestine synthesis byproducts and related sulfur substituted α-alkylthioamphetamines. Bioorg. Med. Chem., 1 Jun 2010, 18 (11), 4009–4031. 1.2 MB. https://doi.org/10.1016/j.bmc.2010.04.022
Cloonan, SM; Keating, JJ; Butler, SG; Knox, AJS; Jørgensen, AM; Peters, GH; Rai, D; Corrigan, D; Lloyd, DG; Williams, DC; Meegan, MJ. Synthesis and serotonin transporter activity of sulphur-substituted α-alkyl phenethylamines as a new class of anticancer agents. Eur. J. Med. Chem., 1 Dec 2009, 44 (12), 4862–4888. 1.2 MB. https://doi.org/10.1016/j.ejmech.2009.07.027
Błachut, D; Wojtasiewicz, K; Krawczyk, K; Maurin, J; Szawkało, J; Czarnocki, Z. Identification and synthesis of by-products found in 4-methylthioamphetamine (4-MTA) produced by the Leuckart method. Forensic Sci. Int., 10 Mar 2012, 216 (1–3), 108–120. 643 kB. https://doi.org/10.1016/j.forsciint.2011.09.005
Nichols, DE. Legal highs: the dark side of medicinal chemistry. Nature, 6 Jan 2011, 469 (7328), 7. 75 kB. https://doi.org/10.1038/469007a
Nichols, DE. The costs of putting knowledge into the wrong hands. Sci. News, 26 Feb 2011, 179 (5), 32. 2.8 MB. https://doi.org/10.1002/scin.5591790529
Fierro, A; Osorio-Olivares, M; Cassels, BK; Edmondson, DE; Sepúlveda-Boza, S; Reyes-Parada, M. Human and rat monoamine oxidase-A are differentially inhibited by (S)-4-alkylthioamphetamine derivatives: Insights from molecular modeling studies. Bioorg. Med. Chem., 1 Aug 2007, 15 (15), 5198–5206. 1.2 MB. https://doi.org/10.1016/j.bmc.2007.05.021 #1
King, LA. New phenethylamines in Europe. Drug Test. Anal., 1 Jul 2014, 6 (7-8), 808-818. 472 kB. https://doi.org/10.1002/dta.1570
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Simmler, LD; Liechti, ME. Pharmacology of MDMA- and amphetamine-like new psychoactive substances. In New Psychoactive Substances: Pharmacology, Clinical, Forensic and Analytical Toxicology; Maurer, HH; Brandt, SD, Eds., Springer, Berlin, Heidelberg, 1 Jan 2018; pp 143-164. 298 kB. https://doi.org/10.1007/164_2018_113
Hurtado-Guzmán, C; Fierro, A; Iturriaga-Vásquez, P; Sepúlveda-Boza, S; Cassels, BK; Reyes-Parada, M. Monoamine oxidase inhibitory properties of optical isomers and N-substituted derivatives of 4-methylthioamphetamine. J. Enzyme Inhib. Med. Chem., 1 Aug 2003, 18 (4), 339–347. 149 kB. https://doi.org/10.1080/1475636031000118437 #MTA
Gobbi, M; Funicello, M; Gerstbrein, K; Holy, M; Moya, PR; Sotomayor, R; Forray, MI; Gysling, K; Paluzzi, S; Bonanno, G; Reyes-Parada, M; Sitte, HH; Mennini, T. N,N-Dimethyl-thioamphetamine and methyl-thioamphetamine, two non-neurotoxic substrates of 5-HT transporters, have scant in vitro efficacy for the induction of transporter-mediated 5-HT release and currents. J. Neurochem., 1 Jun 2008, 105 (5), 1770–1780. 589 kB. https://doi.org/10.1111/j.1471-4159.2008.05272.x #MTA
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Walline, CC; Nichols, DE; Carroll, FI; Barker, EL. Comparative molecular field analysis using selectivity fields reveals residues in the third transmembrane helix of the serotonin transporter associated with substrate and antagonist recognition. J. Pharmacol. Exp. Ther., 1 Jun 2008, 325 (3), 791–800. 269 kB. https://doi.org/10.1124/jpet.108.136200 #4-Methylthioamphetamine
Luethi, D; Liechti, ME. Monoamine transporter and receptor interaction profiles in vitro predict reported human doses of novel psychoactive stimulants and psychedelics. Int. J. Neuropsychoph., 1 Oct 2018, 21 (10), 926–931. 254 kB. https://doi.org/10.1093/ijnp/pyy047 #S1 Phenethylamines 4-MTA
Bork, W; Dahlenburg, R; Gimbel, M; Jacobsen-Bauer, A; Zörntlein, S. Herleitung Von Grenzwerten Der „nicht Geringen Menge“ Im Sinne Des Btmg. Toxichem Krimtech, 1 Jan 2019, 86 (1), 5–91. 4.4 MB. #PP-032
Hägele, JS; Basrak, M; Schmid, MG. Enantioselective separation of novel psychoactive substances using a Lux® AMP 3 μm column and HPLC-UV. J. Pharm. Biomed. Anal., 5 Feb 2020, 179, 112967. 3.6 MB. https://doi.org/10.1016/j.jpba.2019.112967 #A6 LC
Clancy, L; Philp, M; Shimmon, R; Fu, S. Development and validation of a color spot test method for the presumptive detection of 25-NBOMe compounds. Drug Test. Anal., 19 Aug 2020, 13 (5), 929-943. 11.3 MB. https://doi.org/10.1002/dta.2905 #4-methylthioamphetamine
Borenstein, S. Scientist haunted by misuse of drugs he invented. JCLIC, 1 Jan 2011, 21 (1), 3-4. 368 kB. #MTA