6-Norlysergic acid, 6-allyl-N,N-diethylamide · 6-Norlysergamide, 6-allyl-N,N-diethyl · N,N-Diethylnorlysergamide, 6-allyl · N-(6)-Allylnorlysergic acid, N,N-diethylamide · 9,10-Didehydro-6-allyl-N,N-diethylergoline-8β-carboxamide · N-Allyl-nor-LSD
SYNTHESIS: To a solution of 66 mg 2CO3 and 30 mg allyl bromide. When TLC analysis indicated that the nor-LSD had been consumed (30 min) all volatiles were removed under a hard vacuum. The residue was solubilized in CHCl3 (5×5 mL) and the pooled extracts dried over anhydrous Na2SO4 which was remove by filtration. The filtrate removed under vacuum leving leaving a residual white solid. This was separated into two components by centrifugal chromatography (alumina, CH2Cl2, nitrogen and ammonia atmosphere), the first of which was the major product. After removal of the solvent, this was dissolved in hot benzene, filtered and cooled. The addition of hexane prompted crystallization of AL-LAD (N-allyl-nor-LSD) as a white crystalline product weighing 66 mg, yield 88%. It had a mp of 88–90°C and an [α]D +41.8° (c 0.44, EtOH).
DOSAGE: 80–160 micrograms, orally
DURATION: 6–8 h.
QUALITATIVE COMMENTS: (with 50 μg, orally) “I am aware in twenty minutes, and am into a stoned place, not too
(with 80 μg, orally) “I had a mild effect, although the doors to my repressed feelings somehow really become opened up. There was nothing transcendental here, but there were moments where I felt a conscious separation from the world about me. None of the profound meanings that I had hoped to have explained were explained.”
(with 150 μg, orally) “I felt it in less than a quarter hour, and was shooting up past a +++ in another quarter hour. Fast. Just like
(with 150 μg, orally) “Simply beautiful. Erotic and music absorption after second hour. Clear thinking with superb imagery and good interpretation. Easy, gentle sleeping. Next day—serene, clear-thinking peacefulness. One of the best materials ever.”
(with 160 μg, orally) “I took 160 ug micrograms at 11 a.m. on an empty stomach and lay down to listen to a hypnotic relaxing tape, with eye shades and headphones. The onset was very gradual over two or three hours. There was some visual distortion similar to
(with 160 μg, orally) “I pretreated myself with 40 milligrams of Inderal 40 minutes beforehand, took the AL-LAD, and went to bed with eye-shades and ear-phones. There was a very slow onset. The effects were best described as very short bursts of loss of contact with my body, which became increasingly intense and frequent as things progressed. It became really trippy, like acid. There were no visuals with my eyes closed, but when I removed my eye-shades the floors were melting, and the wall patterns and the wood ceiling really flowed. My body felt very blob-like, and I had to get help from my sitter to get up so I could pee. I was very affected by music. There was a very long down-ramp, with physical excitation appearing to linger longer than psychic excitation. Pretty much out of it by 12 hours and I felt well the next day.”
(with 200 μg, orally) “This was taken on the tail end (seventh hour) of an
EXTENSIONS AND COMMENTARY: This is one of the several very potent compounds in a large series of 5-alkylated analogues of nor-LSD analogues of . Most of them proved to be less potent than
A comment is appropriate concerning the use of the prefix “nor,” as in the name of this material N-allyl-nor-LSD and of its immediate precursor, N-ohne-Radical” meaning N (the nitrogen) without the radical (meaning the alkyl group). The removing of the N-methyl group of
13 May 2016 · · Isomer Design
About TiHKAL · info
This version of Book II of TiHKAL is based on the Erowid online version created by Bo Lawler with the help of Erowid, from content generously provided in electronic format by the Authors.
The Erowid online version does not always align precisely with the printed version. Text appears to have been inserted, deleted, or changed at various points. Where the two are seen to diverge both the Erowid and print versions are given. Sharp-eyed readers are encouraged to report novel discrepancies.
As with PiHKAL, I’ve again attempted to reproduce the typographic style of the printed edition. I’ve again made minor changes to some chemical names in line with current nomenclature practice. Typically the change is little more than expanding a prefix or setting it in italics. The history page has further details.
“At the present time, restrictive laws are in force in the United States and it is very difficult for researchers to abide by the regulations which govern efforts to obtain legal approval to do work with these compounds in human beings.“No one who is lacking legal authorization should attempt the synthesis of any of the compounds described in these files, with the intent to give them to man. To do so is to risk legal action which might lead to the tragic ruination of a life. It should also be noted that any person anywhere who experiments on himself, or on another human being, with any of the drugs described herein, without being familiar with that drug’s action and aware of the physical and/or mental disturbance or harm it might cause, is acting irresponsibly and immorally, whether or not he is doing so within the bounds of the law.”
The copyright for Book I of TiHKAL has been reserved in all forms and it may not be distributed. Book II of TiHKAL may be distributed for non-commercial reproduction provided that the introductory information, copyright notice, cautionary notice and ordering information remain attached.
TiHKAL is the extraordinary record of the authors’ years exploring the chemistry and transformational power of tryptamines. This book belongs in the library of anyone seeking a rational, enlightened and candid perspective on psychedelic drugs.
Though Sasha and Ann have put Book II of TiHKAL in the public domain, available to anyone, I strongly encourage you to buy a copy. We owe them — and there’s still nothing quite like holding a real book in your hands.
TiHKAL (ISBN 0-9630096-9-9) is available for US$24.50 (plus $10 domestic first-class shipping) from Transform Press.Transform Press,
Berkeley, CA 94701
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