Exploring Meperidine. To explore a different substance…

Names:
Meperidine
Pethidine
IUPAC name:
Ethyl 1-methyl-4-phenylpiperidine-4-carboxylate
5450 · C15H21NO2 · 247.333
InChI=1S/C15H21NO2/c1-3-18-14(17)15(9-11-16(2)12-10-15)13-7-5-4-6-8-13/h4-8H,3,9-12H2,1-2H3
XADCESSVHJOZHK-UHFFFAOYSA-N This stereoisomer Any stereoisomer

Janssen, PAJ; Eddy, NB. Compounds related to pethidine--IV. New general chemical methods of increasing the analgesic activity of pethidine. J. Med. Chem., 1 Feb 1960, 2 (1), 31–45. 520 kB. https://doi.org/10.1021/jm50008a003 #Pethidine

Casy, AF; Beckett, AH; Hall, GH; Vallance, DK. Chemistry and pharmacology of 4-alkoxy-piperidines related to reversed esters of pethidine. J. Med. Chem., 1 Dec 1961, 4 (3), 535–551. 891 kB. https://doi.org/10.1021/jm50019a012

Janssen, PAJ; Jageneau, AHM; Demoen, PJA; van De. Westeringh, C; Raeymaekers, AHM; Wouters, MSJ; Sanczuk, S; Hermans, BKF; Loomans, JLM. Compounds related to pethidine--I. Mannich bases derived from norpethidine and acetophenones. J. Med. Chem., 1 Feb 1959, 1 (1), 105–120. 695 kB. https://doi.org/10.1021/jm50002a008 #46

Nichols, DE. Dark classics in chemical neuroscience: Lysergic acid diethylamide (LSD). ACS Chem. Neurosci., 20 Feb 2018, n/a. 1.1 MB. https://doi.org/10.1021/acschemneuro.8b00043

2C-G-5
MPPP (opioid)
4-MeO-PBP
2C-D-butterFLY
ED-pyr-A
PLY
EPH · Ethylphenidate
O-2418
2770
4-Me-MPH · 4-Methylmethylphenidate
MXE · Methoxetamine
3-Methylmethylphenidate
Ketobemidone
3,4-MD-PCE
9646
24 September 2018 · Creative Commons BY-NC-SA ·