Exploring 5-HO-α-MT. To explore a different substance…

Names:
5-HO-α-MT
α-Methylserotonin
5-Hydroxy-α-methyltryptamine
IUPAC name:
3-(2-Aminopropyl)-1H-indol-5-ol
5177 · C11H14N2O · 190.242
InChI=1S/C11H14N2O/c1-7(12)4-8-6-13-11-3-2-9(14)5-10(8)11/h2-3,5-7,13-14H,4,12H2,1H3
LYPCGXKCQDYTFV-UHFFFAOYSA-N This stereoisomer Any stereoisomer

Acuña-Castillo, C; Villalobos, C; Moya, PR; Sáez, P; Cassels, BK; Huidobro-Toro, JP. Differences in potency and efficacy of a series of phenylisopropylamine/phenylethylamine pairs at 5-HT2A and 5-HT2C receptors. Br. J. Pharmacol., 1 Jun 2002, 136 (4), 510–519. 232 kB. https://doi.org/10.1038/sj.bjp.0704747

Nichols, DE; Lloyd, DH; Johnson, MP; Hoffman, AJ. Synthesis and serotonin receptor affinities of a series of enantiomers of α-methyltryptamines: Evidence for the binding conformation of tryptamines at serotonin 5-HT1B receptors. J. Med. Chem., 1 Jan 1988, 31 (7), 1406–1412. 1.1 MB. https://doi.org/10.1021/jm00402a026

Glennon, RA; Hong, S; Bondarev, M; Law, H; Dukat, M; Rakhit, S; Power, P; Fan, E; Kinneau, D; Kamboj, R; Teitler, M; Herrick-Davis, K; Smith, C. Binding of O-alkyl derivatives of serotonin at human 5-HT1Dβ receptors. J. Med. Chem., 5 Jan 1996, 39 (1), 314–322. 193 kB. https://doi.org/10.1021/jm950498t

May, JA; Dantanarayana, AP; Zinke, PW; McLaughlin, MA; Sharif, NA. 1-((S)-2-Aminopropyl)-1H-indazol-6-ol: A potent peripherally acting 5-HT2 receptor agonist with ocular hypotensive activity. J. Med. Chem., 12 Jan 2006, 49 (1), 318–328. 124 kB. https://doi.org/10.1021/jm050663x #2

May, JA; Chen, H; Rusinko, A; Lynch, VM; Sharif, NA; McLaughlin, MA. A novel and selective 5-HT2 receptor agonist with ocular hypotensive activity: (S)-(+)-1-(2-Aminopropyl)-8,9-dihydropyrano[3,2-e]indole. J. Med. Chem., 2003, 46 (19), 4188–2195. 126 kB. https://doi.org/10.1021/jm030205t #2b

N-HO-NMT
2-HO-NMT
4-HO-NMT
5-HO-NMT · Norbufotenine
5-MeO-T
4-HO-α-MT
1-Me-5-HT
4-MeO-T
5245
6-HO-AMT
2-Methylseroronin
HOT-T
4,4′-DMAR
3,4-DMAR · 3,4-Dimethylaminorex
10851
4-Ethylaminorex
10075
10074
10073
3,4-DMAR
4,4-DMAR
N,N-DMAR
BNZP
24 June 2018 · Creative Commons BY-NC-SA ·