Exploring AL-LAD. To explore a different substance…

N-(6)-Allylnorlysergic acid, N,N-diethylamide
6-Norlysergamide, 6-allyl-N,N-diethyl
6-Norlysergic acid, 6-allyl-N,N-diethylamide
N,N-Diethylnorlysergamide, 6-allyl
IUPAC name:
ID: 5001 · Formula: C22H27N3O · Molecular weight: 349.469
InChI: InChI=1S/C22H27N3O/c1-4-10-25-14-16(22(26)24(5-2)6-3)11-18-17-8-7-9-19-21(17)15(13-23-19)12-20(18)25/h4,7-9,11,13,16,20,23H,1,5-6,10,12,14H2,2-3H3/t16-,20-/m1/s1
InChI Key: JCQLEPDZFXGHHQ-OXQOHEQNSA-NThis stereoisomerAny stereoisomer

Hoffman, AJ; Nichols, DE. Synthesis and LSD-like discriminative stimulus properties in a series of N(6)-alkyl norlysergic acid N,N-diethylamide derivatives. J. Med. Chem., 1 Jan 1985, 28 (9), 1252–1255. 583 kB. https://doi.org/10.1021/jm00147a022

Watts, VJ; Mailman, RB; Lawler, CP; Neve, KA; Nichols, DE. LSD and structural analogs: Pharmacological evaluation at D1 dopamine receptors. Psychopharmacology, 1 Jan 1995, 118 (4), 401–409. 1.4 MB. https://doi.org/10.1007/BF02245940

Brandt, SD; Kavanagh, PV; Westphal, F; Elliott, SP; Wallach, J; Colestock, T; Burrow, TE; Chapman, SJ; Stratford, A; Nichols, DE; Halberstadt, AL. Return of the lysergamides. Part II: Analytical and behavioural characterization of N6-allyl-6-norlysergic acid diethylamide (AL-LAD) and (2′S,4′S)-lysergic acid 2,4-dimethylazetidide (LSZ). Drug Test. Analysis, 1 Jan 2017, 9 (1), 38-50. 1.6 MB. https://doi.org/10.1002/dta.1985 Open access DOI

Chapman, SJ; Burns, D; Burrow, TE. 1H and 13C NMR spectra of N6-allyl-6-norlysergic acid diethylamide (AL-LAD). BLOTTER, 15 Jul 2016, 2 (1). 23.7 MB. https://doi.org/10.16889/isomerdesign-3 Open access DOI

Brandt, SD; Kavanagh, PV; Twamley, B; Westphal, F; Elliott, SP; Wallach, J; Stratford, A; Klein, LM; McCorvy, JD; Nichols, DE; Halberstadt, AL. Return of the lysergamides. Part IV: Analytical and pharmacological characterization of lysergic acid morpholide (LSM-775). Drug Test. Analysis, 27 Jul 2017, n/a-n/a. 1.2 MB. https://doi.org/10.1002/dta.2222

Stachulski, AV; Nichols, DE; Scheinmann, F. Stereochemical and NMR reassignment of 6-norlysergic acid diethylamide and 6-nor-6-allyllysergic acid diethylamide. J. Chem. Research (S), 1 Jan 1996, 30–31. 4.0 MB.

Anon. New drugs in Europe, 2015, European Monitoring Centre for Drugs and Drug Addiction, 1 May 2016. 1.0 MB. #28

25 May 2018 · Creative Commons BY-NC-SA ·