Fentanyl
 
N-Phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide
 10715 ·  C22H28N2O ·  336.471
 Fentanyl
 InChI=1S/C22H28N2O/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19/h3-12,21H,2,13-18H2,1H3
 PJMPHNIQZUBGLI-UHFFFAOYSA-N This stereoisomer Any stereoisomer
 CCC(=O)N(c1ccccc1)C1CCN(CC1)CCc1ccccc1

Breindahl, T; Kimergård, A; Findal Andreasen, M; Pedersen, DS. Identification of a new psychoactive substance in seized material: the synthetic opioid N-phenyl-N-[1-(2-phenethyl)piperidin-4-yl]prop-2-enamide (Acrylfentanyl). Drug Test. Analysis, 1 Mar 2017, 9 (3), 415-422. 516 kB. https://doi.org/10.1002/dta.2046

Rojkiewicz, M; Majchrzak, M; Celiński, R; Kuś, P; Sajewicz, M. Identification and physicochemical characterization of 4-fluorobutyrfentanyl (1-((4-fluorophenyl)(1-phenethylpiperidin-4-yl)amino)butan-1-one, 4-FBF) in seized materials and post-mortem biological samples. Drug Test. Analysis, 1 Mar 2017, 9 (3), 405-414. 614 kB. https://doi.org/10.1002/dta.2135

Ziporyn, T. A growing industry and menace: makeshift laboratory’s designer drugs. JAMA, 12 Dec 1986, 256 (22), 3061–3063. 486 kB. https://doi.org/10.1001/jama.1986.03380220011003

Ohta, H; Suzuki, S; Ogasawara, K. Studies on Fentanyl and Related Compounds IV. Chromatographic and Spectrometric Discrimination of Fentanyl and its Derivatives. J. Anal. Toxicol., 1 Jul 1999, 23 (4), 280-285. 354 kB. https://doi.org/10.1093/jat/23.4.280 #2

Suzuki, S. Studies on fentanyl and related compounds: II. Spectrometric discrimination of five monomethylated fentanyl isomers by gas chromatography/Fourier transform-infrared spectrometry. Forensic Sci. Int., 1 Sep 1989, 43 (1), 15–19. 289 kB. https://doi.org/10.1016/0379-0738(89)90117-5 #a

Spahn, V; Vecchio, GD; Labuz, D; Rodriguez-Gaztelumendi, A; Massaly, N; Temp, J; Durmaz, V; Sabri, P; Reidelbach, M; Machelska, H; Weber, M; Stein, C. A nontoxic pain killer designed by modeling of pathological receptor conformations. Science, 3 Mar 2017, 355 (6328), 966–969. 2.8 MB. https://doi.org/10.1126/science.aai8636 The erratum and revised supplementary material are appended

Vuckovic, S; Prostran, M; Ivanovic, M; Dosen-Micovic, L; Todorovic, Z; Nesic, Z; Stojanovic, R; Divac, N; Mikovic, Z. Fentanyl analogs: Structure-activity-relationship study. Curr. Med. Chem., 1 Jul 2009, 16 (19), 2468–2474. 211 kB. https://doi.org/10.2174/092986709788682074 #1

Anand, JP; Montgomery, D. Multifunctional opioid ligands. In Handbook of Experimental Pharmacology; , Springer Berlin Heidelberg, 1 Jan 2018; . 362 kB. https://doi.org/10.1007/164_2018_104

Mallette, JR; Casale, JF; Toske, SG; Hays, PA. Characterization of (2R,4S)- and (2R,4R)-2-methylfentanyl and their differentiation from cis- and trans-3-methylfentanyl. Forensic Chem., 1 May 2018, 8 64–71. 1.6 MB. https://doi.org/10.1016/j.forc.2018.02.001 #Fentanyl GC,MS,NMR,IR,other

Higashikawa, Y; Suzuki, S. Studies on 1-(2-phenethyl)-4-(N-propionylanilino)piperidine (fentanyl) and its related compounds. VI. Structure-analgesic activity relationship for fentanyl, methyl-substituted fentanyls and other analogues. Forensic Toxicol., 1 Jun 2008, 26 (1), 1–5. 283 kB. https://doi.org/10.1007/s11419-007-0039-1 #1

EMCDDA. Report on the risk assessment of N-phenyl-N-[1-(2-phenylethyl)piperidin-4- yl]oxolane-2-carboxamide (THF-F), European Monitoring Centre for Drugs and Drug Addiction, 1 Jul 2018. 549 kB. #Fentanyl

EMCDDA. Report on the risk assessment of N-(4-fluorophenyl)-2-methyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide (4F-iBF), European Monitoring Centre for Drugs and Drug Addiction, 1 Jul 2018. 1.2 MB. #Fentanyl

EMCDDA. Report on the risk assessment of N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]furan-2-carboxamide (Furanylfentanyl), European Monitoring Centre for Drugs and Drug Addiction, 1 Dec 2017. 728 kB. #Fentanyl

EMCDDA. Report on the risk assessment of N-(1-phenethylpiperidin-4-yl)-phenylacrylamide (Acryloylfentanyl), European Monitoring Centre for Drugs and Drug Addiction, 1 Dec 2017. 919 kB. #Fentanyl MS,NMR,IR

5663
5669
5683
1-Bn-5-MeO-DET
5836
α-Methyl-acetylfentanyl
4″-Methyl-acetylfentanyl
N-Benzyl-butyrylfentanyl
p-Methyl-acetylfentanyl
o-Methyl-acetylfentanyl
N-Benzyl-3-methylfentanyl
13 November 2018 · Creative Commons BY-NC-SA ·