Explore MDP2P | TiHKAL

ChemSpider 70776
PubChem 78407
Wikidata Q411580
Wikipedia 3,4-Methylenedioxyphenylpropan-2-one
Rhodium Electrochemical Wacker oxidation of safrole (Improvement)
Rhodium The complete book of ecstacy
Rhodium MDP2P from (iso)safrole via epoxide intermediate
Rhodium Reductive amination of ketones to primary amines using NH_4Cl/NaBH₄
Rhodium Electrolytic oxidation of safrole to MDP2P
Rhodium Epoxidation of safrole, using H_2O₂ and a peroxotungstate catalyst
Rhodium Peracid (performic/peracetic) oxidation of isosafrole to MDP2P (Review)
Rhodium Oxidation of propenylbenzenes to P2P′s using peracetic acid
Rhodium Tin(II)Chloride reduction of phenylnitropropenes to P2P′s
Rhodium Electroreductive arylation of chloroacetone to P2P (8)
Rhodium Procedure for the oxidation of isosafrole to MDP2P using oxone
Rhodium Purification of MDP2P via its NaI complex
Rhodium MDP2P from piperonal via 3,4-methylenedioxyphenyl-2-nitropropene
Rhodium MDP2P by 2-nitropropene alkylation of 1,3-benzodioxole
Rhodium MDMA and MDA via the Leuckart reaction
Rhodium Impurities in commercially available MDP2P
Rhodium MDP2P from isosafrole via the dibromide, bromohydrin and epoxide
Rhodium A study of the precursors, intermediates and reaction byproducts in the synthesis of MDMA
Rhodium Complete MDMA synthesis by Dr Drool
Rhodium MDE synthesis via reductive amination with nitroethane
Rhodium MDE synthesis via reductive amination with ethylamine
Rhodium MDA from MDP2P via the oxime, reduced by sodium metal
Rhodium MDA by reductive amination with sodium cyanoborohydride
Rhodium Manufacture of MDA analogs by Dal Cason (really comprehensive)
Rhodium The characterization of some MDA analogs (9)
Rhodium Alkyl halides to carbonyls using 2-Nitropropane (for example bromosafrole to MDP2P)
Rhodium MDMA precursors from eugenol
Rhodium Electrochemical rearrangement of isosafrole epoxide to MDP2P
Rhodium Complete MDMA synthesis by Bright Star
Rhodium TMA-2 from calamus oil, using Wacker oxidation and Leuckart amination
aipsin.com 3,4-Methylenedioxyphenyl-2-propanone (Iss. 9, Sep 2020: X-84)

Phenethylamine: Von der Strucktur zur Funktion PIPAC: 7.5 573

Collins, M; Heagney, A; Cordaro, F; Odgers, D; Tarrant, G; Stewart, S. Methyl 3-[3′,4′-(methylenedioxy)phenyl]-2-methyl glycidate: an ecstasy precursor seized in Sydney, Australia J. Forensic Sci., 1 Jul 2007, 52 (4), 898–903. 714 kB. https://doi.org/10.1111/j.1556-4029.2007.00480.x #3,4-MDP2P GC,MS,NMR,IR

Shulgin, AT. Basic Pharmacology and Effects In Hallucinogens. A Forensic Drug Handbook; Laing, R; Siegel, JA, Eds., Academic Press, London, 24 Apr 2003; pp 67–137. 6.3 MB.

Shulgin, AT; Jacob, P. 1-(3,4-Methylenedioxyphenyl)-3-aminobutane: A potential toxicological problem Clin. Toxicol., 1 Jan 1982, 19 (1), 109–110. 77 kB. https://doi.org/10.3109/15563658208990371 #1

Doughty, D; Painter, B; Pigou, P; Johnston, MR. The synthesis and investigation of impurities found in clandestine laboratories: Baeyer-Villiger route part II; Synthesis of phenyl-2-propanone (P2P) analogues from substituted benzaldehydes Forensic Chem., 1 Jun 2018, 9, 1–11. 2.1 MB. https://doi.org/10.1016/j.forc.2018.03.007 #5g GC,MS,NMR,other

Chambers, SA; DeSousa, JM; Huseman, ED; Townsend, SD. The DARK side of total synthesis: Strategies and tactics in psychoactive drug production ACS Chem. Neurosci., 17 Oct 2018, 9 (10), 2307–2330. 8.1 MB. https://doi.org/10.1021/acschemneuro.7b00528 #161

Dal Cason, TA. The characterization of some 3,4-methylenedioxyphenylisopropylamine (MDA) analogs J. Forensic Sci., 1 Jul 1989, 34 (4), 928–961. 734 kB. https://doi.org/10.1520/JFS12722J #9 Rhodium. GC,MS,NMR,IR

Noggle, FT; Clark, CR; DeRuiter, J. Gas chromatographic and mass spectrometric analysis of samples from a clandestine laboratory involved in the synthesis of ecstacy from sassafras oil J. Chromatogr. Sci., 1 Apr 1991, 29 (4), 168–173. 1.1 MB. https://doi.org/10.1093/chromsci/29.4.168 GC,MS

Hauser, FM; Pütz, M; Rößler, T; Hulshof, JW. Identification of specific markers for amphetamines synthesized from glycidic acid pre‐precursors and retrospective search in German profiling database Drug Test. Anal., 27 Nov 2019, 12 (1), 41-52. 1.5 MB. https://doi.org/10.1002/dta.2686 #PMK GC,MS,NMR

Sorokin, V; Beljaev, A; Ponkratov, K. Expert examination of MDA JCLIC, 1 Jul 1993, 3 (3), 13-15. 556 kB. IR

Davis, S; Vallely, P. Short communication: A novel synthesis of 3,4-methylenedioxyphenyl-2-propanone (MDP2P) from helional JCLIC, 1 Jul 2017, 27 (3), 21-23. 486 kB. #4 GC

Hugel, J; Robertson, C. The synthesis of MDMA and methamphetamine from the corresponding ketones, methylamine hydrochloride, and sodium borohydride JCLIC, 1 Jan 2007, 17 (1), 15-25. 707 kB. MS,IR

Hugel, J. Debriefing of convicted drug producer JCLIC, 1 Jan 2000, 10 (1), 23-26. 532 kB. #MD-P-2-P

Plummer, CM; Breadon, TW; Pearson, JR; Jones, OAH. The synthesis and characterisation of MDMA derived from a catalytic oxidation of material isolated from black pepper reveals potential route specific impurities Sci. Justice, 1 May 2016, 56 (3), 223–230. 630 kB. https://doi.org/10.1016/j.scijus.2016.01.003 #8 GC,NMR

Dunlap, LE; Andrews, AM; Olson, DE. DARK classics in chemical neuroscience: 3,4-Methylenedioxymethamphetamine ACS Chem. Neurosci., 17 Oct 2018, 9 (10), 2408–2427. 940 kB. https://doi.org/10.1021/acschemneuro.8b00155 #12

Philp, M; Shimmon, R; Stojanovska, N; Tahtouh, M; Fu, S. Development and validation of a presumptive colour spot test method for the detection of piperazine analogues in seized illicit materials Anal. Methods, 1 Jan 2013, 5 (20), 5402. 783 kB. https://doi.org/10.1039/c3ay40511g #3,4-Methylenedioxyphenyl-2-propa MS,NMR,IR,spot

Nair, JB; Hakes, L; Yazar-Klosinski, B; Paisner, K. Fully validated, multi-kilogram cGMP synthesis of MDMA ACS Omega, 11 Jan 2022, 7 (1), 900–907. 2.6 MB. https://doi.org/10.1021/acsomega.1c05520 #4 other

Butterick, JR. Synthesis of O-transmethylated catecholamines and psychodysleptic β-phenylisopropylamines Ph. D. Thesis, Simon Faser University, Burnaby, BC, Canada, 11 Mar 1975. 6.1 MB. #49 External examiner: A. T. Shulgin! NMR,IR,UV,TLC

Shulgin, AT; Jacob, P. Potential misrepresentation of 3,4-methylene-dioxyamphetamine (MDA). A toxicological warning J. Anal. Toxicol., 1 Jan 1982, 6 (2), 71–75. 5.6 MB. https://doi.org/10.1093/jat/6.2.71 #1 GC,MS,IR

Al-Hossaini, AM. GC-MS and GC-IRD studies on ethoxyphenethylamines related to MDEA, MDMMA and MBDB Ph. D. Thesis, Auburn University, Auburn, AL, USA, 18 Dec 2009. 1.2 MB. #K7 GC,MS,IR

2Me3Ph glycidate · 2Me3Ph glycidic acid

3′,4′-Methylenedioxypropanophenone

Safrole oxide

11918

11921

12859

3,4-(Dimethylmethylenedioxy)benzaldehyde · 3,4-DMMDBAL