4-MEC
4-Methylethcathinone
 
2-(Ethylamino)-1-(4-methylphenyl)propan-1-one
 2372 ·  C12H17NO ·  191.269
 InChI=1S/C12H17NO/c1-4-13-10(3)12(14)11-7-5-9(2)6-8-11/h5-8,10,13H,4H2,1-3H3
 ZOXZWYWOECCBSH-UHFFFAOYSA-N This stereoisomer Any stereoisomer
 CCNC(C(=O)c1ccc(cc1)C)C

Brandt, SD; Sumnall, HR; Measham, F; Cole, JC. Analyses of second-generation ‘legal highs’ in the UK: Initial findings. Drug Test. Analysis, 1 Aug 2010, 2 (8), 377–382. 317 kB. https://doi.org/10.1002/dta.155

Jankovics, P; Váradi, A; Tõlgyesi, L; Lohner, S; Németh-Palotás, J; Kőszegi-Szalai, H. Identification and characterization of the new designer drug 4′-methylethcathinone (4-MEC) and elaboration of a novel liquid chromatography-tandem mass spectrometry (LC-MS/MS) screening method for seven different methcathinone analogs. Forensic Sci. Int., 15 Jul 2011, 210 (1–3), 213–220. 899 kB. https://doi.org/10.1016/j.forsciint.2011.03.019

Zuba, D. Identification of cathinones and other active components of ‘legal highs’ by mass spectrometric methods. Trends Anal. Chem., 1 Feb 2012, 32, 15–30. 576 kB. https://doi.org/10.1016/j.trac.2011.09.009

Zuba, D; Byrska, B. Prevalence and co-existence of active components of ‘legal highs’. Drug Test. Analysis, 1 Jun 2013, 5 (6), 420–429. 1.3 MB. https://doi.org/10.1002/dta.1365

Gil, D; Adamowicz, P; Skulska, A; Tokarczyk, B; Stanaszek, R. Analysis of 4-MEC in biological and non-biological material—Three case reports. Forensic Sci. Int., 10 May 2013, 228 (1–3), e11–e15. 554 kB. https://doi.org/10.1016/j.forsciint.2013.03.011

Kanu, AB; Brandt, SD; Williams, MD; Zhang, N; Hill, HH. Analysis of psychoactive cathinones and tryptamines by electrospray ionization atmospheric pressure ion mobility time-of-flight mass spectrometry. Anal. Chem., 17 Sep 2013, 85 (18), 8535–8542. 1.6 MB. https://doi.org/10.1021/ac401951a

Iversen, L; Gibbons, S; Treble, R; Setola, V; Huang, X; Roth, BL. Neurochemical profiles of some novel psychoactive substances. Eur. J. Pharmacol., 30 Jan 2013, 700 (1–3), 147–151. 490 kB. https://doi.org/10.1016/j.ejphar.2012.12.006

Glennon, RA. Bath salts, mephedrone, and methylenedioxypyrovalerone as emerging illicit drugs that will need targeted therapeutic intervention. Adv. Pharmacol., 2014, 69, 581–620. 564 kB. https://doi.org/10.1016/B978-0-12-420118-7.00015-9

EMCDDA. New drugs in Europe, 2010, European Monitoring Centre for Drugs and Drug Addiction, 1 May 2011. 700 kB.

Gwak, S; Arroyo-Mora, LE; Almirall, JR. Qualitative analysis of seized synthetic cannabinoids and synthetic cathinones by gas chromatography triple quadrupole tandem mass spectrometry. Drug Test. Analysis, 1 Feb 2015, 7 (2), 121-130. 1.1 MB. https://doi.org/10.1002/dta.1667 #3

Zawilska, JB; Andrzejczak, D. Next generation of novel psychoactive substances on the horizon – A complex problem to face. Drug Alcohol Depend., 1 Jan 2015, 157, 1-17. 3.0 MB. https://doi.org/10.1016/j.drugalcdep.2015.09.030

Leffler, AM; Smith, PB; de Armas, A; Dorman, FL. The analytical investigation of synthetic street drugs containing cathinone analogs. Forensic Sci. Int., 1 Jan 2014, 234, 50-56. 973 kB. https://doi.org/10.1016/j.forsciint.2013.08.021

Fornal, E. Study of collision-induced dissociation of electrospray-generated protonated cathinones. Drug Test. Analysis, 1 Jul 2014, 6 (7-8), 705-715. 527 kB. https://doi.org/10.1002/dta.1573 #6

Kavanagh, PV; Power, JD. New psychoactive substances legislation in Ireland – Perspectives from academia. Drug Test. Analysis, 1 Jul 2014, 6 (7-8), 884-891. 1.2 MB. https://doi.org/10.1002/dta.1598

Rojek, S; Kłys, M; Maciów-Głąb, M; Kula, K; Strona, M. Cathinones derivatives-related deaths as exemplified by two fatal cases involving methcathinone with 4-methylmethcathinone and 4-methylethcathinone. Drug Test. Analysis, 1 Jul 2014, 6 (7-8), 770-777. 444 kB. https://doi.org/10.1002/dta.1615

Vidal Giné, C; Espinosa, IF; Vilamala, MV. New psychoactive substances as adulterants of controlled drugs. A worrying phenomenon? Drug Test. Analysis, 1 Jul 2014, 6 (7-8), 819-824. 113 kB. https://doi.org/10.1002/dta.1610

Griffiths, P; Evans-Brown, M; Sedefov, R. Getting up to speed with the public health and regulatory challenges posed by new psychoactive substances in the information age: Editorial. Addiction, 1 Jan 2013, 108 (10), 1700-1703. 93 kB. https://doi.org/10.1111/add.12287

Jebadurai, J; Schifano, F; Deluca, P. Recreational use of 1-(2-naphthyl)-2-(1-pyrrolidinyl)-1-pentanone hydrochloride (NRG-1), 6-(2-aminopropyl) benzofuran (Benzofury/6-APB) and NRG-2 with review of available evidence-based literature. Hum. Psychopharmacol. Clin. Exp., 1 Jul 2013, 28 (4), 356–364. 612 kB. https://doi.org/10.1002/hup.2302

Nycz, JE; Malecki, G; Zawiazalec, M; Pazdziorek, T. X-ray structures and computational studies of several cathinones. J. Mol. Struct., 14 Sep 2011, 1002 (1), 10–18. 1.1 MB. https://doi.org/10.1016/j.molstruc.2011.06.030 #1a

Adamowicz, P; Zuba, D. Discrimination among designer drug isomers by chromatographic and spectrometric methods. In Chromatographic Techniques in the Forensic Analysis of Designer Drugs; Kowalska, T; Sajewicz, M; Sherma, J, Eds., CRC Press, Taylor & Francis Group, 1 Jan 2018; pp 211–232. 1.1 MB.

Gaspar, H; Bronze, S; Oliveira, C; Victor, BL; Machuqueiro, M; Pacheco, R; Caldeira, MJ; Santos, S. Proactive response to tackle the threat of emerging drugs: Synthesis and toxicity evaluation of new cathinones. Forensic Sci. Int., 1 Sep 2018, 290 146–156. 1.6 MB. https://doi.org/10.1016/j.forsciint.2018.07.001 #4-MEC MS,NMR

Nagashima, M; Suzuki, J; Moriyasu, T; Yoshida, M; Shimizu, M; Hamano, T; Nakae, D. Analysis of uncontrolled drugs purchased in the fiscal year 2010. Ann. Rep. Tokyo Metr. Inst. P. H., 1 Jan 2011, 62 99–105. 889 kB. #4MEC LC,MS,NMR,UV,other

Saha, K; Partilla, JS; Lehner, KR; Seddik, A; Stockner, T; Holy, M; Sandtner, W; Ecker, GF; Sitte, HH; Baumann, MH. ‘Second-generation’ mephedrone analogs, 4-MEC and 4-MePPP, differentially affect monoamine transporter function. Neuropsychopharmacology, 1 May 2015, 40 (6), 1321–1331. 738 kB. https://doi.org/10.1038/npp.2014.325 #4-MEC

3,4-DMMC
4-Me-MABP · 4-Methylbuphedrone
4-EMC · 4-Ethylmethcathinone
7,6-MMAT
NEB
Pentedrone
PAP · Propylcathinone
i-PAP
IBF5MAP
MMAT
EHAT
Phendimetrazine
Isopentedrone
6-MAPDB
5-MAPDB
EMC
2743
2729
3,5-DMMC
2,6-DMMC
2,5-DMMC
2,4-DMMC
2,3-DMMC
G-130
3,6-DMPM
10594
AMMT
PMMA-AT
ALLMA
10532
3-MEC
4-MPM
Phenetrazine
PDM-35 · 5-Methylphenmetrazine
4-MDMC
3-EMC
2-EMC
2-MEC
3-MPM
2-MPM
DMB
3-Methylbuphedrone
17 November 2018 · Creative Commons BY-NC-SA ·