Exploring 25CN-NBF. To explore a different substance…

Names:
25CN-NBF
NBF-2CCN
IUPAC names:
4-(2-{[(2-Fluorophenyl)methyl]amino}ethyl)-2,5-dimethoxybenzonitrile
4-{2-[(2-Fluorobenzyl)amino]ethyl}-2,5-dimethoxybenzonitrile
ID: 1272 · Formula: C18H19FN2O2 · Molecular weight: 314.354
InChI: InChI=1S/C18H19FN2O2/c1-22-17-10-15(11-20)18(23-2)9-13(17)7-8-21-12-14-5-3-4-6-16(14)19/h3-6,9-10,21H,7-8,12H2,1-2H3
InChI Key: QAYYSFNKTHOOBZ-UHFFFAOYSA-NThis stereoisomerAny stereoisomer

Hansen, M. Design and synthesis of selective serotonin receptor agonists for positron emission tomography imaging of the brain. Ph. D. Thesis, University of Copenhagen, 16 Dec 2012. 7.9 MB.

Leth-Petersen, S; Bundgaard, C; Hansen, M; Carnerup, MA; Kehler, J; Kristensen, JL. Correlating the metabolic stability of psychedelic 5-HT2A agonists with anecdotal reports of human oral bioavailability. Neurochem. Res., 12 Feb 2014, 39 (10), 2018-2023. 625 kB. https://doi.org/10.1007/s11064-014-1253-y

Jensen, AA; McCorvy, JD; Leth-Petersen, S; Bundgaard, C; Liebscher, G; Kenakin, TP; Bräuner-Osborne, H; Kehler, J; Kristensen, JL. Detailed characterization of the in vitro pharmacological and pharmacokinetic properties of N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine (25CN-NBOH), a highly selective and brain-penetrant 5-HT2A receptor agonist. J. Pharmacol. Exp. Ther., 1 Jun 2017, 361 (3), 441–453. 4.1 MB. https://doi.org/10.1124/jpet.117.239905 #25CN-NBF

Hansen, M; Phonekeo, K; Paine, JS; Leth-Petersen, S; Begtrup, M; Bräuner-Osborne, H; Kristensen, JL. Synthesis and structure–activity relationships of N-benzyl phenethylamines as 5-HT2A/2C agonists. ACS Chem. Neurosci., 19 Mar 2014, 5 (3), 243-249. 1.4 MB. https://doi.org/10.1021/cn400216u #6c

27 May 2018 · Creative Commons BY-NC-SA ·