Activity of psychedelics

Substance Dosage Duration Remarks Source
5–50 mg Trachsel et al. p. 773
as Amphetamine
>32 mg; >25 mg (R-isomer) [short] Trachsel et al. p. 832
150–230 mg 4–8 h Entaktogen
empathogen-entactogen		 Trachsel et al. p. 556
>400 mg Trachsel et al. p. 826
Pure DRI with no NMDA antagonist or opioid effects, active stimulant at 30 mg, although somewhat mild and uninspiring. jw-pcp
50–80 mg ~8 h Trachsel et al. p. 832
>4 mg Trachsel et al. p. 832
20–40 mg 20–30 h Trachsel et al. p. 900
as 2C-G-N
Slightly more potent than ketamine by weight, 100 mg is strong dose, but effects otherwise similarly favourable and duration about the same. jw-pcp
>300 mg [unknown] Trachsel et al. p. 773
as TMPEA
60–80 mg 12–18 h Starke Imagery (CEV); Musik stimuliert Fantasy; Keine OEV
strong imagery (CEV); music stimulates fantasy; no OEV		 Trachsel et al. p. 715
>300 mg Trachsel et al. p. 884
as TMPEA-6
~25 mg ~5 h Trachsel et al. p. 768
180–360 mg 10–12 h Trachsel et al. p. 705
180–360 mg [12 h] Trachsel et al. p. 698
More potent and longer lasting than ketamine, but less euphoric and lacks the warmth and friendly glow, instead feeling somewhat cold and unwelcoming. jw-pcp
40–80 mg 6–12 h Farbverstärkung; manche CEV/OEV; teilweise körperliches Unbehagen
color enhancement; some CEV/OEV; partial physical discomfort		 Trachsel et al. p. 711
as DFE
50–100 mg 12–18 h Verstärkte Fantasy; Deutliche Visuals; Akustischer Stimulus erzeugt starke Imagery; Beeinträchtigtes Warme-empfinden (Frösteln); Übelkeit
reinforced fantasy; clear visuals; acoustic stimulus produces strong imagery; impaired warm-feeling (shivering); nausea		 Trachsel et al. p. 710
>20 mg Trachsel et al. p. 827
40–60 mg 8–12 h Verstärkte Fantasy jedoch wenig visuelle oder akustische Stimulation; Körperliches Unbehagen; Folgetage: antriebslos, Müdigkeit
reinforced fantasy but little visual or acoustic stimulation; physical discomfort; following days: unmotivated, fatigue		 Trachsel et al. p. 728
>90 mg kurz
short		 Trachsel et al. p. 556
150–250 mg 4–6 h Trachsel et al. p. 585
as Ethylone
75 mg or more ~6 h Nicht vollständig erforscht; keine CEV/OEV mit bis zu 75 mg
not fully explored; no CEV/OEV up to 75 mg		 Trachsel et al. p. 711
as FE
60–150 mg 3–5 h skurril; Schwache visuelle Verstärkung; keine CEV/OEV; Tendenz zu körperlichem Unbehagen
whimsical; weak visual reinforcement; no CEV/OEV; tendency to physical discomfort		 Trachsel et al. p. 712
as FP
60–100 mg 10–14 h nur wenig Visuals; Keine verstärkte Fantasy; body stone
only a few visuals; no enhanced fantasy; body stone		 Trachsel et al. p. 715
40–80 mg 8–12 h Ekstatisch, euphorisch, aktivierend; Keine Visuals; keine CEV; manchmal Übelkeit
ecstatic, euphoric, activating; no visuals; no CEV; sometimes nausea		 Trachsel et al. p. 714
180–360 mg 10–12 h Farbverstärkend Visuals; Musik: grösstenteils Imagery; Geometrisierung von Objekten; Körperliches Unbehagen; Übelkeit
color enhancing visuals; music: mostly imagery; geometrization of objects; physical discomfort; nausea		 Trachsel et al. p. 728
as Mescaline
40–65 mg 12–16 h Starke visuelle Veränderungen (OEV); Deutliche CEV Komplex
strong visual changes (OEV); distinct CEV complex		 Trachsel et al. p. 715
180–210 mg 4–6 h Entaktogen
empathogen-entactogen		 Trachsel et al. p. 556
85 mg ~8 h Deutliches körperliches Unbehagen; Folgetage: Sehr antriebslos
significant physical discomfort; following days: very unpowered		 Trachsel et al. p. 719
>30 mg Nicht bekannt
unknown		 Trachsel et al. p. 555
as METHYL-H
>8 mg [probably rather long] Trachsel et al. p. 835
160 mg 8 h Trachsel et al. p. 830
as 6-Me-MDA
>70 mg [unknown] Trachsel et al. p. 829
>8 mg Trachsel et al. p. 745
Effects similar to PCP but shorter lasting. jw-pcp
30–60 mg 10–12 h Trachsel et al. p. 705
Active with around half the potency of PCP. jw-pcp
Stronger than PCDM, but still less potent than PCP. jw-pcp
“Loses activity dramatically”, half the potency of PCP, and qualitatively weaker. jw-pcp
“Really strong, more potent than PCP for sure so 15 mg blows my mind.” Noted to have favourable subjective effects, but foul taste and smell, harsh and unpleasant to smoke, more body load and nausea. jw-pcp
Sold as street drug, presumably active. jw-pcp
Prototypical arylcyclohexylamine against which all others are compared. Potent NMDA antagonist, fairly strong stimulant, but only weak opioid. Active at 5–15 mg. jw-pcp
Similar potency to PCP, less nausea than PCE but otherwise similar effects. jw-pcp
Active at 10 mg, similar potency to PCP but milder effects, more sedating. jw-pcp
>150 mg [unknown] Trachsel et al. p. 705
unknown unknown TiHKAL #52
250 mg intravenously very short TiHKAL #53
Active at 5 mg, fast onset, more potent than PCP, but less euphoric and notably more potent as dissociative. jw-pcp
35–65 mg 12–18 h Verstärkte Fantasy; Starke CEV; deutliche OEV; wenig body load
reinforced fantasy; strong CEV; significant OEV; little body load		 Trachsel et al. p. 711
as TFE
15–40 mg 14–24 h Visuals; anorektisch; Hinweise auf dissoziative Effekte
visuals; anorexic; indications of dissociative effects		 Trachsel et al. p. 710
60 mg or more ungenügend erforscht
insufficiently researched		 Trachsel et al. p. 712
as TFP
“Inactive up to 3 mg.” jw-nbome
>150 mg [10–16 h] Trachsel et al. p. 824
14 Jan 2018 · ·