TiHKAL · info home
Browse the short index of TiHKAL tryptamines. Read book II of TiHKAL.
Search for tryptamines and related structures. Beyond TiHKAL—selected works by Sasha and others. Explore tryptamine structures and analogues.
Alkaloids of the peyote cactus Log of changes made to this site and differences from the printed version.
PiHKAL · info home
Dear reader: PiHKAL • info, now well into its 2nd decade, is having a mid-life crisis. It has become surly, uncooperative and stubborn despite all my threats, shouting, and jumping about. Teenagers!

Right then, off to Bootstrap-camp with it! To shape up and become responsive! Still, this process of… iterative refinement may take some time. Thank you for your patience while PiHKAL • info unlearns what it has learned. · Comments or suggestions are always welcome.

Cover of TiHKAL: The Continuation. Alexander & Ann Shulgin Cover art by Pamela Engebretson TiHKAL · info is a visual index and map of “TiHKAL: The Continuation,” by Alexander & Ann Shulgin. In TiHKAL the authors continue their exploration (begun in “PiHKAL: A Chemical Love Story”) of the chemistry and transformative power of psychedelic drugs, devoting this volume to tryptamines, β-carbolines, and LSD analogues.

TiHKAL (the book) contains detailed reports on 55 substances and perhaps a hundred more are touched on. Still other tryptamines not discussed in the book are known or are suspected to have psychedelic potential. TiHKAL · info is my attempt to map out the terrain.

Numbering of the Tryptamine skeletonAll tryptamines on this website are drawn with the ring locants arranged counterclockwise starting at the (indole) nitrogen, shown at left. This is the standard numbering for tryptamines, and the order used in TiHKAL.

Alexander “Sasha” Shulgin passed away June 2, 2014 at 5 pm. More at the Erowid Alexander Shulgin Vault.
29 April 2016 · Creative Commons BY-NC-SA ·


trypt-amine\'trip-ta-,mēn\ n. [tryptophan fr. tryptic, fr. trypsin, fr. Gk. tryein, to wear down (from its occurence in pancreatic juice as a proteolytic enzyme) + amine fr. NL ammonia] 1: A naturally occurring compound found in both the animal and plant kingdoms. It is an endogenous component of the human brain. 2: Any of a series of compounds containing the tryptamine skeleton, and modified by chemical constituents at appropriate positions in the molecule.

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TiHKAL · info Statistics

3672 Total
2654 Phenethylamine
652 Tryptamine
114 Lysergamide
89 Other
77 β-Carboline
58 Isoquinoline
28 Undefined