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Browse the short index of TiHKAL tryptamines. Read book II of TiHKAL
Search for tryptamines and related structures Beyond TiHKAL—Selected writings by Sasha and others. Explore tryptamine structures and analogues
The alkaloids of the peyote cactus. How TiHKAL • info differs from the printed version
Go to PiHKAL • info home

Cover of TiHKAL: The Continuation, by Alexander & Ann Shulgin Cover art by Pamela Engebretson TiHKAL • info is a visual index and map of “TiHKAL: The Continuation,” by Alexander & Ann Shulgin. In TiHKAL the authors continue their exploration (begun in “PiHKAL: A Chemical Love Story”) of the chemistry and transformative power of psychedelic drugs, devoting this volume to tryptamines, β-carbolines, and LSD analogues.

TiHKAL (the book) contains detailed reports on 55 substances and perhaps a hundred more are touched on. Still other tryptamines not discussed in the book are known or are suspected to have psychedelic potential. TiHKAL • info is my attempt to map out the terrain.

Numbering of the Tryptamine skeletonAll tryptamines on this website are drawn with the ring locants arranged counterclockwise starting at the (indole) nitrogen, shown at left. This is the standard numbering for tryptamines, and the order used in TiHKAL.

Alexander “Sasha” Shulgin passed away June 2, 2014 at 5 pm. More at the Erowid Alexander Shulgin Vault.
21 November 2015 · Creative Commons BY-NC-SA ·


trypt-amine\'trip-ta-,mēn\ n. [tryptophan fr. tryptic, fr. trypsin, fr. Gk. tryein, to wear down (from its occurence in pancreatic juice as a proteolytic enzyme) + amine fr. NL ammonia] 1: A naturally occurring compound found in both the animal and plant kingdoms. It is an endogenous component of the human brain. 2: Any of a series of compounds containing the tryptamine skeleton, and modified by chemical constituents at appropriate positions in the molecule.

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Absorbing bits of material

TiHKAL • info Statistics

3672 Total
2654 Phenethylamine
652 Tryptamine
114 Lysergamide
89 Other
77 β-Carboline
58 Isoquinoline
28 Undefined